Winning with the Parasite outbreak in Normal mode is easy and getting to the solution in Brutal mode is just as easy following the same strategy. The process is slow as well as for the Mushroom in which you have to wait for the whole world to be infected but you will have the help of the unlocked genes. Gene modifiers are unlocked after completing certain levels and since Parasite is an unlocked level, it means that you have completed previous levels and therefore have access to some modifiers.
Steps
Part 1 of 4: Starting the Game
Step 1. Create a New Game
Choose New Game and then tap "Parasite".
If you have previously saved a game, it will be replaced and will no longer be recoverable. Select "Brutal Mode" for this level and then name your epidemic
Step 2. Edit the Genetic Code
In this part, you will be able to assign a custom genetic code to your outbreak. Genes are unlocked only after completing the previous levels.
- You can follow this guide on how to modify the Genetic Code, but you can choose any gene that you think is effective for this level.
- Under DNA Genes, choose Cytochrome discharge. This upgrade will give you more DNA points when you pop bubbles.
- In Traveling Geniuses, it is advisable to choose Teracito as it increases the chances of the epidemic spreading by land. It can cross borders as long as there are many infected.
- The Evolution Gene should be Sinto-stasis. This gene will make it easier to cure the outbreak but later the symptoms will not require more DNA points to develop. This is a very important part of the strategy. You will not have to worry about the Healing percentage in this level as we will be using a "silent" approach until the epidemic has infected the whole world.
- Choose Genetic Imitation as the mutating gene. This upgrade will make it harder to heal the Parasite, a good choice to offset the negative effects of Synto-stasis.
- Finally, Extremophile is the best choice as an Environmental Gene. This gene will give you a small bonus in all environments, giving your Parasite a slight advantage when it enters countries with different types of climates.
Part 2 of 4: Making the First Approach
Step 1. Start in India
It is the country of choice for most Plague Inc. players due to its high population and access to ports and airports. China is another good alternative, but at some levels of the game China may be very slow in spreading the epidemic.
- If you choose India, the first country to be infected will most likely be China. From there, the epidemic will spread faster and more effectively as there are already a good number of infected in India.
- After choosing the starting country, pop the red and orange bubbles to collect DNA points.
- Don't forget to fast-forward the game. You can find this option at the top right.
Step 2. Evolve Symbiosis
Remember that each type of epidemic has its own unique ability that can bring enormous benefits. The Parasite possesses Symbiosis, an ability that makes the parasite more compatible with the infected, making it more difficult to detect; evolve it to level 3.
- Keep popping the bubbles until you have enough DNA points.
- Do not add symptoms or transmissions until you have evolved Symbiosis to the maximum.
Step 3. Evolve Cyst and Anemia
After evolving Symbiosis up to level 3, you can evolve Cyst and Anemia now. You can find these Symptoms in the Disease window, on the Symptoms screen.
- Cysts are bubbles containing pockets of pathogen, which have a slight chance of bursting and spreading the parasite further. Put simply, this symptom helps to increase the infectivity level of the epidemic.
- Anemia is a decrease in the number of red blood cells and hemoglobin which can lead to organ hypoxia. This also increases the infectivity of the pathogen.
- Generally, evolving Symptoms at this early stage will make humans aware of the epidemic, leading them to conduct research on the cure before you have had a chance to infect the whole world, but with the Parasite Symbiosis skill, the symptoms of level 1 and 2 are hardly identifiable.
Step 4. Evolve Air and Water
Since we have evolved Cysts, it is time to exploit the pathogen. As mentioned earlier, cysts contain pockets of pathogen which is released when they burst.
To increase infectivity, we must evolve Air and Water. These Genes can be found on the Transmissions screen. Evolve Water at level 1 and Air at level 2
Step 5. Involve lethal Symptoms
There is a chance that the outbreak will develop random symptoms, which is not a problem as no DNA points are needed, but make sure you involve the lethal symptoms.
"Lethal" Symptoms will alarm researchers as they start working on a cure that will eradicate your epidemic so be sure to keep lethal symptoms under control
Part 3 of 4: Adding Resistance
Step 1. Evolve Drug Resistance
As you may have noticed, the spread of the epidemic is still slow despite the high level of transmission. The reason is the fact that people can use medicines to fight the parasite.
To prevent this, evolve Drug Resistance 1. You can find it on the Skills screen. Your epidemic will dramatically spread to other countries at a satisfactory rate, especially in poor countries
Step 2. Evolve Resistance to cold
One of the obstacles to spread to other countries is the climate. Evolve Cold Resistance up to level 2.
- This ability will strengthen your Parasite, which will be able to spread to cold countries like Canada, Greenland, etc. Don't forget to involve lethal symptoms.
- There is no need to evolve Heat Resistance as your epidemic started in India - it is already immune to hot climates. Save these DNA points for a later stage of the game.
Step 3. Evolve Hypersensitivity
If this symptom hasn't evolved on its own, use your DNA points to do so. Again, this symptom increases the infectivity of the pathogen.
Once this is done, return to the game, pop more bubbles and wait for all nations to be infected or wait for the message "There are no more healthy people in the world" to appear on the screen
Part 4 of 4: Exterminating the Human Race
Step 1. Evolve lethal symptoms
Immediately after receiving the message about the total absence of healthy people in the world, it is time to evolve the lethal symptoms.
Go to the Symptoms screen and evolve the following: Paralysis, Total Organic Collapse and Coma. This series will start killing and the cure will begin to progress as well
Step 2. Use the extra DNA points
As soon as the population begins to be decimated, you will receive a generous amount of DNA points. Use them to evolve Internal Hemorrhage, Hemorrhagic Shock and Necrosis. Don't worry about the cure rate.
Step 3. Keep the Healing level low
All nations will be working together to find a cure. Stop them by evolving the Genetic Strengthening and Genetic Reshuffling skills.
