The Nano Virus is a level of Plague Inc. that is a real race against the cure. As soon as the infection begins, the search for a cure will begin immediately. This means that many of your efforts will be directed towards slowing the cure and spreading the infection without killing anyone. Brutal mode makes everything more difficult but with the right strategy you will be able to pass this level without too much effort.
Steps
Part 1 of 3: Initial Organization
Step 1. When starting a game, you will be able to choose some upgrades for your pathogen
What you choose at this stage will have a major effect on the game you play, so make your choices carefully. Here are some suggestions for upgrades you should choose to make the game easier:
- Genes DNA - Increase in ATP. This upgrade will grant you some extra DNA points at the start of the game, which are essential to slow down the heal.
- Traveling genes - Aquacito. Fundamental for infecting difficult islands such as Greenland, Iceland and New Zealand.
- Genes evolution - Synto-stasis. This upgrade will keep the costs of developing symptoms low.
- Genes in mutation - Genetic imitation. This upgrade will slow down the progress of the cure, which is extremely important as the cure will begin immediately.
- Environmental genes - Extremophile. This upgrade increases the infection rate in all environmental conditions.
Step 2. Purchase some initial upgrades
Before choosing your starting country, take advantage of the ATP Increase bonus to purchase some initial upgrades. These will make your life a lot easier later on and help you slow down the cure.
- Code Snippet Intercept - This will help you slow down the cure.
- Cough
- Cyst
- Abscesses
- Insomnia
- Paranoia
Step 3. Choose a starting country
The starting country is very important, as this will determine how quickly your pathogen will spread. Many guides recommend starting India due to its large population and proximity to China, although others suggest Saudi Arabia.
Research on treatment will begin immediately after choosing the starting country
Part 2 of 3: Infecting the World
Step 1. Evolve essential upgrades
At the start of the game, you should give top priority to certain upgrades that will give you greater chances of winning. As soon as you start collecting DNA points, evolve the following upgrades, in this order and as soon as you can afford them:
- Code segment interception
- Nausea
- He retched
- Drug resistance 1
- Genetic strengthening 1 and 2
Step 2. Deal with sterilization
If you receive information pop-ups about the sterilization of airplanes and ships, you should prioritize the corresponding transmission methods:
- If airplanes are sterilized, evolve Air 1 immediately.
- If the ships are sterilized, immediately evolve Water 1.
Step 3. Slow down the cure
The next upgrades will aim to slow down the progress of the cure. These symptoms should complicate cure research and should evolve as soon as possible:
- Hyper-sensitivity
- Paralysis
- Coma
- Convulsions
- Folly
Step 4. Increase the infection rate
The next few upgrades will make it harder to kill your pathogen and increase the chances of its spread. Quickly evolve the following to increase the rate at which your virus infects new countries and slow down progress on finding a cure:
- Root stabilized elements
- Water 2
- Air 2
- Extreme bioaerosol
- Drug resistance 2
- Cold resistance 1 and 2
Step 5. Evolve other symptoms
Now that the virus is spreading, it's time for more symptoms to evolve. These will increase the rate of infection, leading to an even faster global infection:
- Pneumonia
- Sneezing
- Eczema
- Sweat
- Anemia
- Haemophilia
- Skin lesions
- Diarrhea
Step 6. Strengthen your pathogen
There are still a couple of upgrades that you should turn your attention to if you want to slow down the progress of the cure. These will only be available later in the game:
- Hacked encryption
- Immunity to drugs
Part 3 of 3: Destroy the Population
Step 1. Use Replication Overload
After all countries are infected, this ability can increase the infectivity of your pathogen. The only negative effect is that after a short period of time, the infectivity rate will drop to a level below its original value, so only use it when all countries are infected.
Step 2. Involve the random symptoms
From time to time, your pathogen will randomly mutate. We strongly advise you to involve these symptoms as soon as they appear, as they can kill the world's population before the pathogen has spread everywhere.
Step 3. Scramble your genes
Towards the end of the game, yours will be a race against the cure. The Genetic Reshuffle skill will slow the progress of the cure and is a good investment if you have nothing else to evolve. There are three levels, each of which will reverse the cure.
Step 4. Evolve all symptoms when everyone is infected
When all the people in the world have been infected, you will receive a pop-up message. At this point, you can safely evolve all lethal symptoms, as you don't have to worry about infecting other people. At this point, the sooner you kill everyone, the better.